初步研究 Pilot study

[The study has ended]


Aim and objectives



  1. 探討以部份自費形式推行每日「事前預防用藥」的可接受程度
  2. 分析參加者服藥的依從性
  3. 評估以激勵方式推行「事前預防用藥」的實際性
  4. 試行「事前預防用藥」的監察系統

香港中文大學 – 新界東醫院聯網臨床研究倫理聯席委員會被授權在有需要時審視個人資料藉以評估研究倫理(參考編號:2016.470)。如果你有更多關於臨床 研究倫理相關問題,請與該委員會聯繫(電郵 或 致電 2632 3935)。

The project aims to serve as a feasibility study in making PrEP available to MSM at high risk of infection on a trial basis.

The objectives are, to:

  1. test the acceptability of partially self-financed daily PrEP
  2. examine the pattern of adherence to daily PrEP
  3. evaluate the practicability of an incentivized model for PrEP
  4. trial-run the system for monitoring the use of PrEP.

The Joint Chinese University of Hong Kong – New Territories East Cluster Clinical Research Ethics Committee has approved this study (Ref. No.: 2016.470) and is authorised to access the participants' records related to the study for ethics review purpose. For enquiry regarding clinical research ethics, please contact the Committee at and phone at 2632 3935.

初步研究 Pilot study

研究設計 Study design


Participants will be followed up for 48 weeks. PrEP will be prescribed to participants in the first 30 weeks on a partial payment basis. During this prescription period, participants will have to take medicine daily; visit the clinic regularly for body check-up, HIV and STI tests, complete questionnaire, make payment and collect prescription. At week 48, participants will be contacted for follow-up questionnaire.

參加資格 Eligibility criteria


  1. 為十八歲或以上男性、曾與男性肛交
  2. 經常在港居住
  3. 沒有使用過「事前預防用藥」
  4. 在未來數月有傾向進行不安全性行為
  5. 願意部份自費獲得「事前預防用藥」
  6. 沒有感染愛滋病毒
  7. 乙型肝炎表面抗原呈陰性反應
  8. 腎臟功能正常

To join the study, you must:

  1. be male, aged 18 or above, and had anal sex with another man; and
  2. normally reside in Hong Kong; and
  3. have never used PrEP; and
  4. be inclined to have unprotected anal sex in the coming months; and
  5. be willing to partly pay for PrEP; and
  6. be HIV negative; and
  7. be HBsAg negative; and
  8. have normal renal function

研究流程 Flow chart of the study

*須進行抽血測試 Venipuncture is required.



  • 腎功能
  • 乙型肝炎表面抗原
  • 愛滋病毒
  • 梅毒、淋病、衣原體


Body check-up & tests:

  • Renal function
  • HBsAg
  • HIV
  • Syphilis, NG/CT

Urine samples will be collected.
Fingerprick rapid tests will be performed.

注意: PrEP1研究已經完結。有興趣者可以電郵聯絡
Attention: PrEP1 study has ended. Interested person may contact for updates on new projects.